Thermo Fisher Scientific and Matrix Science Announce an Integrated Solution for Superior Protein Identification

Released on: February 26, 2008, 2:46 am

Press Release Author: Thermo Fisher Scientific - Mass Spectrometry

Industry: Chemicals

Press Release Summary: Thermo Fisher Scientific Inc., the world leader in serving
science, today announced the integration of Matrix Science\'s Mascot search engine
for protein identification with its BioWorks software. The SEQUEST search algorithm
from the University of Washington, (a component of BioWorks software) and Mascot are
the two most widely accepted search engines in the field for protein identification
and PTM characterization.



Press Release Body: Thermo Fisher Scientific Inc., the world leader in serving
science, today announced the integration of Matrix Science\'s Mascot search engine
for protein identification with its BioWorks software. The SEQUEST search algorithm
from the University of Washington, (a component of BioWorks software) and Mascot are
the two most widely accepted search engines in the field for protein identification
and PTM characterization.

This integration will enable users to consolidate identification results from the
two search engines and cross-validate the results, taking advantage of the
complementary information provided by each. Studies have shown that different search
engines match different spectra, resulting in a large overlap and some unique
protein identifications for each. Including both search engines in the same software
platform provides a new level of confidence in protein identification. The new
integration of SEQUEST and Mascot within the Thermo Scientific BioWorks platform
enables the kind of flexibility in mass spectrometry data interrogation that
customers are looking for.

John Cottrell of Matrix Science stated, \"We are delighted that Thermo Fisher
Scientific will enable its customers to purchase Mascot as part of a complete
instrument and software platform\". In addition, Andreas Hhmer, proteomics marketing
director at Thermo Fisher Scientific said, \"It\'s all about flexibility for our
customers - we want to give customers who have already chosen superior
instrumentation the choice to analyze their data with the search engine they prefer,
or to increase their protein coverage by combining the results from both.\"
Integration of Mascot provides users with comprehensive tools for data processing,
protein identification, quantitation and characterization.

For more information about Mascot, visit www.matrixscience.com. For more information
about BioWorks, visit www.thermo.com/bioworks.

Thermo Scientific is part of Thermo Fisher Scientific, the world leader in serving
science.

2008 Thermo Fisher Scientific Inc. All rights reserved. Mascot is a trademark of
Matrix Science Ltd. SEQUEST is a registered trademark of the University of
Washington. All other trademarks are the property of Thermo Fisher Scientific Inc.
and its subsidiaries.

###
About Thermo Fisher Scientific
Thermo Fisher Scientific Inc. (NYSE: TMO) is the world leader in serving science,
enabling our customers to make the world healthier, cleaner and safer. With an
annual revenue rate of more than $9 billion, we employ 30,000 people and serve over
350,000 customers within pharmaceutical and biotech companies, hospitals and
clinical diagnostic labs, universities, research institutions and government
agencies, as well as environmental and industrial process control settings. Serving
customers through two premier brands, Thermo Scientific and Fisher Scientific, we
help solve analytical challenges from routine testing to complex research and
discovery. Thermo Scientific offers customers a complete range of high-end
analytical instruments as well as laboratory equipment, software, services,
consumables and reagents to enable integrated laboratory workflow solutions. Fisher
Scientific provides a complete portfolio of laboratory equipment, chemicals,
supplies and services used in healthcare, scientific research, safety and education.
Together, we offer the most convenient purchasing options to customers and
continuously advance our technologies to accelerate the pace of scientific
discovery, enhance value for customers and fuel growth for shareholders and
employees alike. Visit www.thermofisher.com.

About Matrix Science
Matrix Science develops and markets bioinformatics products and services for mass
spectrometry-based proteomics. Mass spectrometry has become established as the
method of choice for protein analysis, providing levels of speed and sensitivity
that cannot be matched by other techniques. Mascot, Matrix Science\'s lead software
package, searches mass spectrometry data against molecular sequence databases to
identify the constituent proteins and characterize post-translational modifications.
The search procedure is computationally intensive, requiring complex statistical
calculations to be performed rapidly while streaming through large protein and
nucleic acid sequence databases. The company is based in London, UK, and has offices
in Philadelphia, PA and Tokyo, Japan.



Web Site: http://www.thermo.com/bioworks

Contact Details: For further press information please contact: Laura Browne, The
Scott Partnership, 1 Whiteside, Station Road, Holmes Chapel, Cheshire. CW4 8AA
United Kingdom Tel: + 44 1477 539539 Fax: +44 1606 1477 539540 E-mail:
thermo@scottpr.com

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