Global Proliferative Vitreoretinopathy Market Overview with Size, Share, Growth, Industry Demand, Forecast and Application Analysis To 2027

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Dublin 2, Ireland, 2018-Jun-16 — /EPR Network/ — Recently, a novel report developed using proven research methodologies at the headquarters of Fact. MR has identified various prominent factors and trends prompting market growth of Pickleball equipment market. The study is titled as Proliferative Vitreoretinopathy Market Forecast, Trend Analysis & Competition Tracking – Global Review 2018 to 2027”, which deeply analyses the global market trends, with historical data from 2017 and 2018, and projections of compound annual growth rates (CAGRs) during the mentioned forecast of 2017-2028. For the benefit of the readers, the report concludes with a special focus on the detailed profiles of the major vendors in the global proliferative vitreoretinopathy market.

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A recent Fact.MR report foresees the proliferative vitreoretinopathy market to record a moderate rise over the period of forecast (2018-2027). Revenues from treatment and management of proliferative vitreoretinopathy worldwide will reach nearly US$ 660 Mn by 2027-end.

Proliferative Vitreoretinopathy Market: New PVR Development Suppression & Prevention Methods to Underpin Growth

Proliferative vitreoretinopathy, an inflammatory fibrotic disease, stems from inflammatory milieu post-RRD, which in turn prevents retinal healing. Several studies aimed at suppressing or preventing the development of PVR are being conducted worldwide, with some of the recent ones elucidating effect of “substance P (SP),” and targeted use of non-steroidal anti-inflammatory drugs such as “lornoxicam.”

Research carried out on lornoxicam has not only demonstrated successful improvement in the condition of retina and choroid, but also reduced frequency of membrane formation significantly. Studies conducted on substance P have revealed that SP has the capability of inhibiting apoptosis, and epithelial-mesenchymal transition (EMT) induced by TNFα caused, thereby suppressing or preventing development of proliferative retinopathy.

Proliferative Vitreoretinopathy Market: Potential of Systemic Anti-TNFα Treatment in Reduction of PVR to Influence Future Developments

Lack of effective prophylaxis or treatment has made proliferative vitreoretinopathy one of the most devastating complications witnessed in RRD. TNFα has been implied in PVR development, which in turn necessitates blockade of this factor for reducing or preventing onset of proliferative vitreoretinopathy. However, systemic treatment of PVR using anti-TNFα entails several side-effects and risks, and employment of such drugs for PVR treatment is not yet justified. Researchers have sought indirect approaches for determination of effectiveness of anti-TNFα in protection against PVR development post-RRD surgery.

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Despite sound principles on which the approaches are based, low prevalence of patients affected with RRD, chronic inflammatory diseases, and PVR has prevented researchers from drawing conclusions with regard to potential effectiveness of the anti-TNFα therapy as prophylactic treatment for preventing or reducing PVR incidences following RRD. However, these approaches hold promise in promoting future in-vivo studies, and randomizing clinical trials in humans with the help of more preclinical research.

Table of Contents:

1. Executive Summary
1.1. Summarizing Key Findings
1.2. Trends and Developments
1.3. Strategic Themes
1.4. Highlighting Action Area – Wheel of Fortune

2. Global Proliferative Vitreoretinopathy Market Overview
2.1. Introduction
2.2. Market Definition
2.3. Market Taxonomy and Segments Captured

3. Global Proliferative Vitreoretinopathy Market Outlook 
3.1. Market Size (US$ Mn) and Forecast, 2013-2027
3.2. Market Y-o-Y Growth
3.3. Forecast Factors and Relevance Impact

4. Global Proliferative Vitreoretinopathy Market Dynamics
4.1. Drivers
4.2. Restraints
4.3. Opportunities
4.4. Trends

Continued………

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