Atypical Hemolytic Uremic Syndrome-Pipeline Review: Stakeholder Count on Complete Blood Count (CBC) Test

Posted on 2019-09-11 by Mark Hub in Pharmaceuticals // 0 Comments

Albany, USA, 2019-Sep-11 — /EPR Network/ —

Hemolytic uremic syndrome (HUS) is a thrombotic microanglopathy characterized by intravascular hemolysis, acute kidney failure and thrombocytopenia. Atypical hemolytic uremic syndrome (aHUS) is difficult to treat, more severe and can occur with diverse conditions, including autoimmune disease, pneumococcal infections, HIV transplantation, specific drugs and irradiation.

These insights are according to the intelligence report, titled, “Atypical Hemolytic Uremic Syndrome—Pipeline Review, H2 2019,” which has been freshly added to Market Research Hub’s (MRH) exponential repository.

With prevailing TMA syndrome, understanding pertaining to the pathogenesis of a HUS has soared in the recent past. Patients with aHUS usually have subtle and seldom fluctuating symptoms at onset which are preceded by bacterial or viral illness, history of drug intake and connective tissue disease.

According to the present prevailing classifications, aHUS is not linked with coexisting or infectious disease and instead it is linked with an acquired or genetic defect in regulation of complement activation on host cells. Prominently, number of patients with aHUS have either autoantibodies or mutations which are linked with impaired complement regulation.

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The symptoms of aHUS normally happen in flare-ups that are often started by a trigger in the body. While some flare ups of aHUS are mild, severe flare-up may damage kidney and lead to failure. Nevertheless, aHUS can lead to high blood pressure; kidney damage; damage to other organs and heart disease.

Accordingly, the use of complete blood count (CBC) test has increased in the recent years. Further, drug called eculizumab is commonly used for the treatment of atypical hemolytic uremic syndrome.

Atypical Hemolytic Uremic Syndrome-Pipeline Review: Report Synopsis

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