Single Cell Analysis Market: Opportunities and Challenges

CITY, Country, 2019-Nov-13 — /EPR Network/ —

Single cell analysis market is estimated to grow at a CAGR of 16.5% during the forecast period, to reach USD 3.59 Billion by 2022.

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High growth potential of single-cell sequencing (scs)

Single-cell transcriptome/sequencing helps understand the transcriptional stochasticity and cellular heterogeneity in much more detail. It assists in the investigation of small groups of differentiating cells and circulating tumor cells. It also demonstrates the heterogeneity of gene expressions, interaction and regulations of gene regulatory networks, characteristics of putative cancer stem cells, gene expression profiles of intracellular compartments, mRNA locations, and allele-specific gene expression. Advancements in single-cell sequencing have improved the detection and analysis of infectious disease outbreaks, antibiotic drug-resistant strains, food-borne pathogens, and microbial diversities in the environment.

Single-cell sequencing is considered as a powerful tool to identify disease-specific biomarkers to diagnose and monitor the occurrence and progress of a disease, as well as the patient response to treatment. Considering the huge potential of SCS technology, companies are focusing on instruments and reagents suitable for single-cell sequencers. In this regard, Illumina, Inc. (U.S.) offers integrated ultra-low-input and single-cell RNA sequencing workflows (with the SMARTer Ultra Low Input RNA Kit by U.S.-based Clontech Laboratories Inc., combined with the Nextera XT DNA Library Preparation Kit and Illumina sequencing technology) that help in the simplification of the entire process—from library preparation to data analysis and biological interpretation. Considering the high-growth potential of this segment, several other advanced SCS instruments are expected to be developed and launched in the market in the coming years. This presents itself as an opportunity for the single cell analysis market.

Survival of small players and new entrants

The survival of small players and new entrants in the single-cell analysis market is a significant challenge. Established players such as Thermo Fisher Scientific, Inc., Bio-Rad Laboratories, Inc., and Fluidigm Corporation account for a major share of the market. These players have a robust product portfolio and strong brand recognition. As a result, it is difficult for small players and new entrants to compete with established players. Also, as large investments are required for the R&D and launch of innovative products in the market, it is difficult for small players to sustain their operations and compete with established players that have large R&D budgets.

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