Global Folliculotropic Mycosis Fungoides Treatment Market Insights and Trends, Forecast 2021 to 2031
Global Folliculotropic Mycosis Fungoides Treatment Market: Market Outlook
Folliculotropic Mycosis Fungoides is a most common variant of mycosis fungoides (Alibert-Bazin), known as cutaneous T-cell lymphoma. The major symptoms of cutaneous T-cell lymphoma disease are the enlarge lymph nodes severe itching and rashes. The mycosis fungoides can be identified by the skin symptoms like plaques, acneiform lesions, or as a tumor being alopecia and pathches. The early-stage mycosis fungoides grows very slow initially and treated with skin-directed treatment.
But the advanced-stage mycosis fungoides requires more aggressive therapies. The adults aged more than 50 years are more susceptible to this disease. Males are more frequently affected than females. The main cause of the diseases is unidentified. Most of the individuals suffering from this disease have chromosomal abnormalities. The appropriate treatment is mainly dependent on the variety of factors including, the presence of symptoms, stage of the disease, patients condition, and patient’s health background and cost of care.
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According to the study published, Europe and the United States has around 6 Mycosis fungoides cases per million every year. This accounts for 4% of all non-Hodgkin lymphoma cases. It is more common in adults over 50 years of age, with a male: the female ratio between 1.6 and 2.
What are the Key Trends Impacting Growth of the Global Folliculotropic Mycosis Fungoides Treatment Market?
The folliculotropic mycosis fungoides treatment market is brimming with emerging market and government organizations, developing to introduce innovations in the field of biotechnology and life science areas. The growing focus in research & development activities is another trending factor actively adopted by the leading manufacturers and researchers.
The new drug approvals to treat such rare diseases is another key to step towards the folliculotropic mycosis fungoides treatment that expects to serve lucrative opportunities in the folliculotropic mycosis fungoides treatment market. For instance, in June 2020, the European Commission approved Kyowa Kirin Co., Ltd., to commercialize POTELIGEO® (mogamulizumab) in Germany for the treatment of mycosis fungoides in adults. The treatment was applicable for the patients who have already received at least one pre-systemic therapy. POTELIGEO is the first-in-class humanised monoclonal antibody that increases the attraction of immune cells from the immune system to destroy the cancerous cells.
The growing shift towards biologics from therapeutic landscape expects to boost the folliculotropic mycosis fungoides treatment market growth rapidly. The regulatory bodies are recognizing the newly developed product under special drug designation that benefits the vendors that contribute to increasing the sales of folliculotropic mycosis fungoides drugs fueling the folliculotropic mycosis fungoides treatment market growth in the coming years.
What are the Driving Factors that expected to Boost the Global Folliculotropic Mycosis Fungoides Treatment Market growth?
The rising incidence rate of mycosis fungoides among adults is one of the major factors expects to boost the folliculotropic mycosis fungoides treatment market growth worldwide. Rising investment in research areas to develop an effective treatment solution with ongoing clinical studies expects propel the market growth. Collaboration between the hospitals and research labs can benefit the scope of treatment with new findings like novel immunotherapy drugs.
Increasing awareness about the disease, rising large patient population with the weak immune system, growing lymphoma cancer cases are some of the factors influencing the growth of folliculotropic mycosis fungoides treatment market. The growing geriatric population and rise in wealth in developed and developing countries are driving the demand for folliculotropic mycosis fungoides treatment.
However, affluent consumers, being more concerned about health, and raising awareness about early treatment are contributing to the growth of the folliculotropic mycosis fungoides treatment market. The regulatory approvals for special drug designation for treatment, strong R&D pipeline expects to propel the folliculotropic mycosis fungoides treatment market growth in the coming future.
According to the National Institute of Health (NIH), the overall incidence of cutaneous T-cell lymphoma was found to be around 10.2 per million persons. Among which the mycosis fungoides associated cases were found to be more than half of the cutaneous T-cell lymphoma cases, with an incidence of 5.6 per million persons.
What are the Restraining Factors that can Hamper the Global Folliculotropic Mycosis Fungoides Treatment Market Growth
Lack of expertise in developing countries for tailored treatment is the major market restraints for folliculotropic mycosis fungoides treatment market. However the high-cost of the treatments like radiation therapy, chemotherapy, or other photodynamic therapy expects to hamper the folliculotropic mycosis fungoides treatment market growth.
The high exposure to radiation to folliculotropic mycosis fungoides treatment may cause adverse side effects like eczema, rashes, plaque and other skin associated diseases. Thus, the rising adverse effects, the dominance of alternative treatment, and high cost of treatment especially be a cause for concern in emerging markets, hampering the growth of the global folliculotropic mycosis fungoides treatment market.
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Key Segments of Global Folliculotropic Mycosis Fungoides Treatment Market Covered in the Report
Based on type, the global folliculotropic mycosis fungoides treatment market has been segmented as
- Small molecule
- Biologics
Based on drug type, the global folliculotropic mycosis fungoides treatment market has been segmented as
- Topical Steroids
- Antineoplastic agents
- Mechlorethamine
- Bexarotene
- ingenol mebutate
- diclofenac
- Interferons
- Others
Based on therapy, the global folliculotropic mycosis fungoides treatment market has been segmented as
- Radiation Therapy
- Photodynamic Therapy
- Targeted Therapy
- Chemotherapy
- Drug Therapy
- Immunotherapy
- Psoralen Pus Ultraviolet A (PUVA)
- Ultraviolet B (UVB)
Based on end users, the global folliculotropic mycosis fungoides treatment market has been segmented as
- Hospitals
- Speciality clinics
- Others
Based on the region, the global folliculotropic mycosis fungoides treatment market has been segmented as
- North America
- Latin America
- Europe
- South Asia
- East Asia
- Oceania
- Middle East & Africa
Why the Small Molecule Segment Accounted the Highest Share in the Folliculotropic Mycosis Fungoides Treatment Market?
The small molecule segment gained traction and accpunted for highest share in the folliculotropic mycosis fungoides treatment market that was expected to continue over forecast period. These molecules are utilized in combinatorial therapies which are more effective in folliculotropic mycosis fungoides treatment.
The small molecules in cutaneous T-cell lymphomas is their utilization in combination among them or with other types of therapies such as monoclonal antibodies and/or single/polychemotherapy. low cost and easy availability of such molecules are some of the factors witnessing the dominance in the folliculotropic mycosis fungoides treatment market.
Why UVB has Gained Popularity in the Folliculotropic Mycosis Fungoides Treatment Market?
Althpugh the photo therapy is the first line treatment for folliculotropic mycosis fungoides but UVB narrow band (nbUVB) photo therapy gained traction in the folliculotropic mycosis fungoides treatment market as compared to the UV broadband (bbUVB). The efficacy of nbUVB was found to be more and was subsequently confirmend by the number of research studies.
Competitive Landscape
Key players such as
- Takeda Pharmaceutical Company Ltd.
- Merck & Co. Inc.
- Seattle Genetics, Inc.
- Kyowa Kirin Co. Ltd.
- Eisai Co.Ltd.
- Helsinn Healthcare SA
- Horizon Therapeutics plc.
- Celegene Corporation
- Azurity Pharmaceuticals Inc.
- Elorac
- Soligenix
- Actelion pharmaceuticals Ltd.
- Others are actively involved in folliculotropic mycosis fungoides treatment market.
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