Europe, CIS & Africa Spatial Transcriptomics Market 2030: Future Challenges and Opportunities

Market Size & Trends

The Europe, CIS & Africa spatial transcriptomics market size was estimated at USD 93.9 million in 2023 and is projected to grow at a CAGR of 15.57% from 2024 to 2030. The emerging potential of spatial omics analysis for cancer research, the advent of the fourth generation of sequencing (in-situ sequencing), and the increasing funding & collaborative initiatives in spatial biology research are some of the factors that drive the market growth.

The rising prevalence of cancer is a major driving factor in the market. The growing prevalence of such chronic diseases necessitates efficient biomarker discovery and early & accurate diagnosis for effective disease management as well as treatment. In oncology, spatial omics analysis has shown significant promise for enhancing the understanding of tumor heterogeneity, identifying potential biomarkers, and guiding personalized treatment strategies.

Gather more insights about the market drivers, restrains and growth of the Europe, CIS & Africa Spatial Transcriptomics Market

Product Insights

The consumables segment dominated the market in 2023 with a 52.16% share. Its dominance can be attributed to high product penetration, increasing use of reagents & kits, wide product availability, and frequent purchase of consumables to run instruments. The development of any new instrument or upgrade of any existing instrument directly impacts the segment growth as the development of any new instrument will result in the need for developing the required consumables. Genetic research has been revolutionized in recent decades with the introduction of advanced technologies and innovations in sequencing.

Technology Insights

The sequencing-based methods segment dominated the market in terms of revenue in 2023, with a market share of 54.64%, and is anticipated to grow at the fastest over the forecast period. This segment is further categorized into laser capture microdissection (LCM), transcriptome in-vivo analysis (TIVA), in situ sequencing, and microtomy sequencing. Sequencing-based platforms have revolutionized gene expression study by enabling high-dimensional gene expression measurements at spatial resolution. These platforms capture messenger RNA (mRNA) molecules at spatial measurement locations on tissue sections, tag them with unique spatial barcodes, and generate a readout through sequencing. NGS can capture polyadenylated RNA transcripts, enabling the discovery of new differential genes or biological mechanisms.

Workflow Insights

The sample preparation segment dominated the market with a 55.49% share in 2023 and is expected to grow at the fastest CAGR from 2024 to 2030. Sample preparation is crucial for obtaining high-quality sequencing products for performing genomics & transcriptomics studies. Companies launching new products for streamlining and automating the sample preparation procedure are expected to boost segment growth. For instance, in June 2022, 10x Genomics launched Visium CytAssist, a compact, benchtop spatial instrument that can help streamline sample processing. It enables the transfer of analytes from tissue sections premounted on standard glass slides to Visium slides.

Sample Type Insights

The Formalin-Fixed Paraffin-Embedded (FFPE) segment dominated the market with the largest revenue share of 64.57% in 2023. FFPE is a standard sample type widely used to preserve human tissue for clinical diagnosis. It holds the majority share in the market. This technique is considered the best in researching tissue morphology for clinical histopathology & diagnostic purposes. FFPE specimens are abundant in clinical tissue banks, which can be attributed to segment growth. However, they are incompatible with single-cell level transcriptome sequencing owing to RNA degradation & damage during storage and extraction.

End-use Insights

The translational research segment held the largest market share of 56.24% in 2023 and is expected to grow at the fastest CAGR over the forecast period. Spatial transcriptomics plays a crucial role in advancing translational research. This technology enables researchers to analyze gene expression within the context of tissue structure, providing valuable insights into cellular interactions and functions. The integration of spatial transcriptomics into translational research holds significant promise for bridging the gap between basic scientific discoveries and clinical applications. Spatial transcriptomics is used in cancer research for understanding cell-to-cell interaction and tumor progression of different cell types within tumors, including immune cells, stromal cells, and cancer cells.

Country Insights

Europe dominated the market and accounted for a 94.57% share in 2023 owing to the established biotechnology research & development sector, growing focus on spatial biology research, and the presence of key players. Furthermore, significant investments and funding from public and private sources enable the expansion of spatial transcriptomics research & the commercialization of spatial omics products.

Key Europe, CIS & Africa Spatial Transcriptomics Company Insights

Key players operating in the market are undertaking various initiatives to strengthen their market presence and increase the reach of their products and services. Strategies such as expansion activities and partnerships are playing a key role in propelling market growth.

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Key Europe, CIS & Africa Spatial Transcriptomics Companies:

• Illumina, Inc.
• Bruker
• 10X Genomics
• EdenRoc Sciences (Cantata Bio, LLC)
• Shimadzu Corporation
• Waters Corporation
• Bio-Techne
• Vizgen Inc.
• Spatial Genomics
• Akoya Biosciences, Inc

Europe, CIS & Africa Spatial Transcriptomics Market Segmentation

Grand View Research has segmented the Europe, CIS & Africa spatial transcriptomics market based on product, technology, workflow, sample type, end-use, and region:

Europe, CIS & Africa Spatial Transcriptomics Product Outlook (Revenue, USD Million, 2018 – 2030)

• Instruments

• Consumables
• Software

Europe, CIS & Africa Spatial Transcriptomics Technology Outlook (Revenue, USD Million, 2018 – 2030)

• Sequencing-based Methods
• IHC
• Microscopy-based RNA Imaging Techniques

Europe, CIS & Africa Spatial Transcriptomics Workflow Outlook (Revenue, USD Million, 2018 – 2030)

• Sample Preparation
• Instrumental Analysis
• Data Analysis

Europe, CIS & Africa Spatial Transcriptomics Sample Type Outlook (Revenue, USD Million, 2018 – 2030)

• FFPE
• Fresh Frozen

Europe, CIS & Africa Spatial Transcriptomics End-use Outlook (Revenue, USD Million, 2018 – 2030)

• Translational Research
• Academic Customers
• Diagnostic Customers
• Pharmaceutical Manufacturer

Europe, CIS & Africa Spatial Transcriptomics Regional Outlook (Revenue, USD Million, 2018 – 2030)

• Europe
• The Commonwealth of Independent States (CIS)
• Africa

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Recent Developments

• In April 2024, Vizgen expanded its single-cell spatial transcriptomics offering by launching the MERSCOPE Ultra Platform and MERFISH 2.0 chemistry.
• In March 2024, Bruker acquired the optical cell imaging company Phasefocus, further enhancing Bruker’s existing cell imaging product portfolio.
• In February 2024, NanoString (now Bruker) launched the CosMx Human 6K Discovery Panel, enabling researchers to measure over 6,000 RNA targets.
• In February 2024, DNAnexus and Curio Bioscience collaborated to make data analysis simplified and streamlined for whole transcriptome spatial mapping studies.
• In October 2023, Bruker acquired PhenomeX, a provider of research tools for single-cell biology, to strengthen its existing cellular & subcellular analysis tools, including the CellScape spatial biology platform.

About Grand View Research

Grand View Research is a full-time market research and consulting company registered in San Francisco, California. The company fully offers market reports, both customized and syndicates, based on intense data analysis. It also offers consulting services to business communities and academic institutions and helps them understand the global and business scenario to a significant extent. The company operates across multitude of domains such as Chemicals, Materials, Food and Beverages, Consumer Goods, Healthcare, and Information Technology to offer consulting services.

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