Phosphoglucomutase (PGM 1) Deficiency-Market Analysis, Opportunities and Detailed Pipeline Product Profiles

Albany, US, 2019-Jul-19 — /EPR Network/ —Market Research Hub (MRH) has actively discoursed a new study titled “Phosphoglucomutase (PGM 1) Deficiency-Market Insights, Epidemiology and Market” Forecast-2028, added to its vast online repository. The main motive of this assessment is to present clear insights about the growth factor experienced across the Phosphoglucomutase (PGM 1) Deficiency-Market during the forecast period. Readers can access vital information associated to prime market facets such as market size, market share, market drivers, future trends, challenges, opportunities and sales channels. Furthermore, the availability of competitive developments including leading market players make the report a rich data source for investors and new entrants.

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Delve Insights Phosphoglucomutase (PGM 1) Deficiency – Market Insights, Epidemiology and Market Forecast-2028 report delivers an in-depth understanding of the disease, historical & forecasted epidemiology as well as the market trends of IPF in the United States, EU5 (Germany, Spain, Italy, France and United Kingdom), and Japan.

The Report provides the current treatment practices, emerging drugs, market share of the individual therapies, current and forecasted market size of Phosphoglucomutase (PGM 1) Deficiency from 2017 to 2028 segmented by seven major markets. The Report also covers current treatment practice/algorithm, market drivers, market barriers and unmet medical needs to curate best of the opportunities and assess underlying potential of the market.

Geography Covered
The United States
EU5 (Germany, France, Italy, Spain and the United Kingdom)
Japan

Study Period: 2017-2028

Phosphoglucomutase (PGM 1) Deficiency – Disease Understanding and Treatment Algorithm

The DelveInsight PGM-1 deficiency market report gives the thorough understanding of the PGM1 by including details such as disease definition, cause, symptoms, pathophysiology, and diagnostic trends. It also provides treatment algorithms and treatment guidelines for etiology in the US, Europe, and Japan.

Phosphoglucomutase (PGM 1) Deficiency Epidemiology
The Phosphoglucomutase (PGM 1) Deficiency epidemiology division provide the insights about historical and current patient pool and forecasted trend for every eight major countries. It helps to recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders. This part of the Delve Insight report also provides the diagnosed patient pool and their trends along with assumptions undertaken.

The disease epidemiology covered in the report provides historical as well as forecasted epidemiology (total prevalent cases, prevalence of PGM1 deficiency based on clinical manifestations and congenital malformations, and prevalence based on severity) scenario of PGM1 deficiency in the 7MM covering United States, EU5 countries (Germany, Spain, Italy, France and United Kingdom), and Japan from 2017-2028.

According to DelveInsight, total prevalent population of Idiopathic PGM1 deficiency in 7MM markets was found to be 2593 in 2017.

Phosphoglucomutase (PGM 1) Deficiency Drug Chapters
this segment of the PGM1 deficiency encloses the detailed analysis of marketed drugs and late stage (Phase-III and Phase-II) pipeline drugs. It also helps to understand the clinical trial details, expressive pharmacological action, agreements and collaborations, approval and patent details, and the latest news and press releases.

The current strategies for the treatment of PGM-1 deficiency primarily encompass galactose administration along with other off-label symptomatic medications to ensure the overall reduction of associated disease complications. In general, the current mainstays for the PGM-1 deficiency treatment includes dietary supplementation of sugar along with other cardiotonic, complex carbohydrates, hydrocortisone and symptomatic medications to make the affected individuals clinically comfortable. Furthermore, physical, occupational, and speech therapy are additional management modalities that impart clinical benefits to the PGM-1 deficient individuals. Currently two drugs are under development for the treatment of Phosphoglucomutase 1 (PGM1) deficiency. CERC-801 (Cerecor Inc.) an ultra-pure, oral, crystalline formulation of D-galactose and ORL-1G-D-galactose (Orpha Labs) are into eraly phase of clinical development.

Phosphoglucomutase (PGM 1) Deficiency Market Outlook
The PGM1 deficiency market outlook of the report helps to build the detailed comprehension of the historic, current and forecasted trend of the market by analyzing the impact of current therapies on the market, unmet needs, drivers and barriers and demand of better technology.
This segment gives a through detail of market trend of marketed drug and pipeline therapy by evaluating their impact based on annual cost of therapy, inclusion and exclusion criterias, mechanism of action, compliance rate, growing need of the market, increasing patient pool, covered patient segment, expected launch year, competition with other therapies, brand value, their impact on the market and view of the key opinion leaders. The calculated market data are presented with relevant tables and graphs to give a clear view of the market at first sight.

According to Delve Insight, the market of Idiopathic Pulmonary Fibrosis in 7MM was found to be USD 10.86 million in 2017.

Phosphoglucomutase (PGM 1) Deficiency Drugs Uptake
This section focusses on the rate of uptake of the potential drugs in the market during the study period from 2017-2028. The analysis covers market uptake by drugs; patient uptake by therapies and sales of each drug.
This helps in understanding the drugs with the most rapid uptake, reasons behind the maximal use of new drugs and allows the comparison of the drugs on the basis of market share and size which again will be useful in investigating factors important in market uptake and in making financial and regulatory decisions.

Phosphoglucomutase (PGM 1) Deficiency Report Insights
Patient Population
Therapeutic Approaches
Pipeline Analysis
Market Size and Trends
Market Opportunities
Impact of upcoming Therapies

Phosphoglucomutase (PGM 1) Deficiency Report Key Strengths
10 Year Forecast
7MM Coverage
Epidemiology Segmentation
Drugs Uptake
Highly Analyzed Market
Key Cross Competition
Phosphoglucomutase (PGM 1) Deficiency Report Assessment
Current Treatment Practices
Unmet Needs
Detailed Pipeline Product Profiles
Market Attractiveness
Market Drivers and Barriers

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Key Insights
2. Phosphoglucomutase 1 (PGM1) Deficiency Market Overview at a Glance
2.1. Market Share (%) Distribution of PGM1 Deficiency in 2017
2.2. Market Share (%) Distribution of PGM1 Deficiency in 2028
3. Disease Background and Overview
3.1. Introduction
3.2. Facts about Phosphoglucomutase-1
3.3. Pathophysiology
3.4. Causes
3.5. Symptoms
3.6. Multisystem phenotype in PGM1 deficiency
3.7. Diagnosis
4. Epidemiology and Patient Population
4.1. Key Findings
4.2. KOLs Views: Epidemiology
4.3. Assumptions and Rationale 7MM
5. 7MM Total Prevalent Patient Population of PGM1 Deficiency
6. Country Wise-Epidemiology of PGM1 Deficiency
6.1. The United States
6.1.1. Total Prevalent Cases of PGM1 Deficiency in the United States
6.1.2. Prevalence of PGM1 Deficiency based on Clinical Manifestations in the United States
6.1.3. Prevalence of PGM1 Deficiency based on Congenital malformations in the United States
6.1.4. Prevalence of PGM1 Deficiency based on Severity in the United States
6.2. EU5
6.2.1. Germany
6.2.2. Total Prevalent Cases of PGM1 Deficiency in Germany
6.2.3. Prevalence of PGM1 Deficiency based on Clinical Manifestations in Germany
6.2.4. Prevalence of PGM1 Deficiency based on Congenital malformations in Germany
6.2.5. Prevalence of PGM1 Deficiency based on Severity in Germany
6.2.6. France
6.2.7. Total Prevalent Cases of PGM1 Deficiency in France
6.2.8. Prevalence of PGM1 Deficiency based on Clinical Manifestations in France
6.2.9. Prevalence of PGM1 Deficiency based on Congenital malformations in France
6.2.10. Prevalence of PGM1 Deficiency based on Severity in France
6.2.11. Italy
6.2.12. Total Prevalent Cases of PGM1 Deficiency in Italy
6.2.13. Prevalence of PGM1 Deficiency based on Clinical Manifestations in Italy
6.2.14. Prevalence of PGM1 Deficiency based on Congenital malformations in Italy
6.2.15. Prevalence of PGM1 Deficiency based on Severity in Italy
6.2.16. Spain
6.2.17. Total Prevalent Cases of PGM1 Deficiency in Spain
6.2.18. Prevalence of PGM1 Deficiency based on Clinical Manifestations in Spain
6.2.19. Prevalence of PGM1 Deficiency based on Congenital malformations in Spain
6.2.20. Prevalence of PGM1 Deficiency based on Severity in Spain
6.2.21. The United Kingdom
6.2.22. Total Prevalent Cases of PGM1 Deficiency in the UK
6.2.23. Prevalence of PGM1 Deficiency based on Clinical Manifestations in The UK
6.2.24. Prevalence of PGM1 Deficiency based on Congenital malformations in The UK
6.2.25. Prevalence of PGM1 Deficiency based on Severity in The UK
6.3. Japan
6.3.1. Total Prevalent Cases of PGM1 Deficiency in Japan

Continued………….@#

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